Please note that "neither clove oil nor eugenol is approved as a new animal drug to treat or mitigate any diseases in any species in the U.S. Therefore, the use of either clove oil or eugenol as an anesthetic for fish makes them unapproved new animal drugs" according to the U.S, Department of Health and Human Services, Food and Drug Administration, Center for Veterinary Medicine - June 11, 2002 see: www.fda.gov/cvm/guidance/guide150.pdf
The FDA document also states that "eugenol may not be used in any form on animals (fish) that could possibly be consumed by humans..."
The US Fish and Wildlife Service holds an Investigational New Animal Drug (INAD) exemption for the purpose of studying the drug to gather data to support FDA approval. This product has been given an investigational 21 day withdrawal time for the dosing regimen in the current studies, which is the same as exists for the approved fish anesthetic MS-222.
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In an unpublished experiment undertaken by members of our local Trout Unlimited chapter (Ken Preiser, Tom Friedrich, Peter Renne), the investigators found quicker induction and recovery times of fish anaesthetized w/ clove oil vs. MS-222; in addition, there is no withdrawl period associated with clove oil (i.e., fish can be stocked or consumed immediately), and clove oil is about 5x less expensive than MS-222. Also - see Anderson et al. 1997. The use of clove oil as an anesthetic for rainbow trout and its effects on swimming performance. North American Journal of Fisheries Management 17:301-307. hope this helps - Steve
Stephen M.Coghlan Jr.
Teaching Assistant / Research Assistant
248 Illick Hall
State University of New York
College of Environmental Science and Forestry
Syracuse, New York 13210
(315) 470 - 6949
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